There is hope. A new 2 pronged approach has shown 100% tumor removal in mice! Nothing I have read has ever shown 100% success.
Read it here: https://www.fightaging.org/archives/2020/08/trem2-inhibition-as-a-potentially-broadly-effective-cancer-therapy/

On Tuesday, September 1, 2020 at 1:43:13 AM UTC+12, The Judge wrote:
> There is hope. A new 2 pronged approach has shown 100% tumour removal in mice! Nothing I have read has ever shown 100% success.
> Read it here: https://www.fightaging.org/archives/2020/08/trem2-inhibition-as-a-potentially-broadly-effective-cancer-therapy/

This is what's really required. We're not aware of all of the carcinogens
in the environment, nor their consequences for our health . I was wondering a wee while ago as to whether a probe might be made for our
mobile phones that let us monitor pollutants in the environment.

On another related matter, were you caught unawares when your doctor
told you about your illness. Whose responsibility is it to forewarn and
prepare you for these possibilities. If you'd known about this possibility
might you have put in a concerted effort to prevent or prepare; done
something different with your life.
Considering how folding@home.com uses private compute power from
a multitude of individuals, and provides information to the public, the
knowledge is everywhere; except, perhaps, in the doctors clinic.

On Saturday, September 5, 2020 at 10:17:00 AM UTC+12, sciw...@gmail.com wrote:
> On Tuesday, September 1, 2020 at 1:43:13 AM UTC+12, The Judge wrote:
> > There is hope. A new 2 pronged approach has shown 100% tumour removal in mice! Nothing I have read has ever shown 100% success.
> > Read it here: https://www.fightaging.org/archives/2020/08/trem2-inhibition-as-a-potentially-broadly-effective-cancer-therapy/
> This is what's really required. We're not aware of all of the carcinogens
> in the environment, nor their consequences for our health . I was wondering a wee while ago as to whether a probe might be made for our
> mobile phones that let us monitor pollutants in the environment.
>
> On another related matter, were you caught unawares when your doctor
> told you about your illness. Whose responsibility is it to forewarn and
> prepare you for these possibilities. If you'd known about this possibility
> might you have put in a concerted effort to prevent or prepare; done
> something different with your life.
> Considering how fol...@home.com uses private compute power from
> a multitude of individuals, and provides information to the public, the
> knowledge is everywhere; except, perhaps, in the doctors clinic.

On Saturday, September 5, 2020 at 10:17:00 AM UTC+12, sciw...@gmail.com wrote:
> On Tuesday, September 1, 2020 at 1:43:13 AM UTC+12, The Judge wrote:
> > There is hope. A new 2 pronged approach has shown 100% tumour removal in mice! Nothing I have read has ever shown 100% success.
> > Read it here: https://www.fightaging.org/archives/2020/08/trem2-inhibition-as-a-potentially-broadly-effective-cancer-therapy/
> This is what's really required. We're not aware of all of the carcinogens
> in the environment, nor their consequences for our health . I was wondering a wee while ago as to whether a probe might be made for our
> mobile phones that let us monitor pollutants in the environment.
>
> On another related matter, were you caught unawares when your doctor
> told you about your illness. Whose responsibility is it to forewarn and
> prepare you for these possibilities. If you'd known about this possibility
> might you have put in a concerted effort to prevent or prepare; done
> something different with your life.
> Considering how fol...@home.com uses private compute power from
> a multitude of individuals, and provides information to the public, the
> knowledge is everywhere; except, perhaps, in the doctors clinic.

A little unfamiliar with the posting procedures of this site.

Might be of some interest, also allows me to have a record of developments.

Using gold nanoparticles of the right size the large leaky vessels that feed
tumours are selectively targeted, whilst the smaller veins of the rest of the
body are avoided.

Then infra red light, possibly from a laser, is applied. This results in
the ablation of the cancerous material, what remains might then be suceptiblle
to immunotherapy.
Angiogenesis in tumours has been known and studied for decades.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473940/

That's the theory, these are some of the results.

https://www.docwirenews.com/docwire-pick/hem-onc-picks/using-gold-nanoparticles-to-improve-prostate-cancer-treatment/

On Monday, September 21, 2020 at 1:19:13 PM UTC+12, sciw...@gmail.com wrote:
> On Saturday, September 5, 2020 at 10:17:00 AM UTC+12, sciw...@gmail.com wrote:
> > On Tuesday, September 1, 2020 at 1:43:13 AM UTC+12, The Judge wrote:
> > > There is hope. A new 2 pronged approach has shown 100% tumour removal in mice! Nothing I have read has ever shown 100% success.
> > > Read it here: https://www.fightaging.org/archives/2020/08/trem2-inhibition-as-a-potentially-broadly-effective-cancer-therapy/
> > This is what's really required. We're not aware of all of the carcinogens
> > in the environment, nor their consequences for our health . I was wondering a wee while ago as to whether a probe might be made for our
> > mobile phones that let us monitor pollutants in the environment.
> >
> > On another related matter, were you caught unawares when your doctor
> > told you about your illness. Whose responsibility is it to forewarn and
> > prepare you for these possibilities. If you'd known about this possibility
> > might you have put in a concerted effort to prevent or prepare; done
> > something different with your life.
> > Considering how fol...@home.com uses private compute power from
> > a multitude of individuals, and provides information to the public, the
> > knowledge is everywhere; except, perhaps, in the doctors clinic.
> A little unfamiliar with the posting procedures of this site.
>
>
>
> Might be of some interest, also allows me to have a record of developments.
>
>
> Using gold nanoparticles of the right size the large leaky vessels that feed
> tumours are selectively targeted, whilst the smaller veins of the rest of the
> body are avoided.
>
> Then infra red light, possibly from a laser, is applied. This results in
> the ablation of the cancerous material, what remains might then be suceptiblle
> to immunotherapy.
> Angiogenesis in tumours has been known and studied for decades.
>
>
> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473940/
>
>
>
> That's the theory, these are some of the results.
>
> https://www.docwirenews.com/docwire-pick/hem-onc-picks/using-gold-nanoparticles-to-improve-prostate-cancer-treatment/

Considering the availability of different treatment options, all with different efficacies, toxicities;
the construction of a decision tree, or an if...then...else statement seems appropriate.

Then another possibility is a neural network that has, and does, learn from clinical outcomes.
At this level this might not be as complicated as at the drug discovery level.
And of course, all the while, for the patient, doing no harm.

Now clinical trials involve a degree of risk, the FDA is there to regulate these risks and
determine the safety of medications. Time, I think, for them to provide functioning mini
organs in a support medium, derived from the volunteers stem cells, or at least for the
initial screening, something generic.
Maybe after thirty years they're still not up to the task.

On Tuesday, September 22, 2020 at 4:40:20 PM UTC+12, sciw...@gmail.com wrote:
> On Monday, September 21, 2020 at 1:19:13 PM UTC+12, sciw...@gmail.com wrote:
> > On Saturday, September 5, 2020 at 10:17:00 AM UTC+12, sciw...@gmail.com wrote:
> > > On Tuesday, September 1, 2020 at 1:43:13 AM UTC+12, The Judge wrote:
> > > > There is hope. A new 2 pronged approach has shown 100% tumour removal in mice! Nothing I have read has ever shown 100% success.
> > > > Read it here: https://www.fightaging.org/archives/2020/08/trem2-inhibition-as-a-potentially-broadly-effective-cancer-therapy/
> > > This is what's really required. We're not aware of all of the carcinogens
> > > in the environment, nor their consequences for our health . I was wondering a wee while ago as to whether a probe might be made for our
> > > mobile phones that let us monitor pollutants in the environment.
> > >
> > > On another related matter, were you caught unawares when your doctor
> > > told you about your illness. Whose responsibility is it to forewarn and
> > > prepare you for these possibilities. If you'd known about this possibility
> > > might you have put in a concerted effort to prevent or prepare; done
> > > something different with your life.
> > > Considering how fol...@home.com uses private compute power from
> > > a multitude of individuals, and provides information to the public, the
> > > knowledge is everywhere; except, perhaps, in the doctors clinic.
> > A little unfamiliar with the posting procedures of this site.
> >
> >
> >
> > Might be of some interest, also allows me to have a record of developments.
> >
> >
> > Using gold nanoparticles of the right size the large leaky vessels that feed
> > tumours are selectively targeted, whilst the smaller veins of the rest of the
> > body are avoided.
> >
> > Then infra red light, possibly from a laser, is applied. This results in
> > the ablation of the cancerous material, what remains might then be suceptiblle
> > to immunotherapy.
> > Angiogenesis in tumours has been known and studied for decades.
> >
> >
> > https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473940/
> >
> >
> >
> > That's the theory, these are some of the results.
> >
> > https://www.docwirenews.com/docwire-pick/hem-onc-picks/using-gold-nanoparticles-to-improve-prostate-cancer-treatment/
> Considering the availability of different treatment options, all with different efficacies, toxicities;
> the construction of a decision tree, or an if...then...else statement seems appropriate.
>
> Then another possibility is a neural network that has, and does, learn from clinical outcomes.
> At this level this might not be as complicated as at the drug discovery level.
> And of course, all the while, for the patient, doing no harm.
>
> Now clinical trials involve a degree of risk, the FDA is there to regulate these risks and
> determine the safety of medications. Time, I think, for them to provide functioning mini
> organs in a support medium, derived from the volunteers stem cells, or at least for the
> initial screening, something generic.
> Maybe after thirty years they're still not up to the task.

Car t cells certainly are effective for some cancers, as are other types of immunotherapy.
A consideration though , is damage to cells that have similar binding sites protruding
from their lipid membranes, this is where a selection for multiple and unique binding sites
becomes essential; there are a few approaches to this.
To check on the selectivity , a screening for exclusive binding is required; in a medium.

If solid tumours aren't completely eliminated then the possibility of metastatic cancers from
these is always present, how effectively car t cell therapies are going to be against the various
forms of these is, at this time, an unknown.