Rocksolid Light

News from da outaworlds

mail  files  register  groups  login

Message-ID:  

BOFH excuse #398: Data for intranet got routed through the extranet and landed on the internet.

sci / sci.med.pathology / Iron And Lupus

SubjectAuthor
o Iron And Lupusironjustice

1
Subject: Iron And Lupus
From: ironjustice
Newsgroups: sci.med.pathology
Date: Sun, 14 Apr 2019 02:53 UTC
X-Received: by 2002:a37:6d82:: with SMTP id i124mr7847066qkc.22.1555210394681;
Sat, 13 Apr 2019 19:53:14 -0700 (PDT)
X-Received: by 2002:a25:9d8a:: with SMTP id v10mr3838614ybp.90.1555210394583;
Sat, 13 Apr 2019 19:53:14 -0700 (PDT)
Path: eternal-september.org!news.eternal-september.org!reader01.eternal-september.org!reader01.eternal-september.org!feeder.eternal-september.org!weretis.net!feeder6.news.weretis.net!feeder.usenetexpress.com!feeder-in1.iad1.usenetexpress.com!border1.nntp.dca1.giganews.com!nntp.giganews.com!t9no4391143qtn.0!news-out.google.com!i8ni2093qtr.1!nntp.google.com!t9no4391132qtn.0!postnews.google.com!glegroupsg2000goo.googlegroups.com!not-for-mail
Newsgroups: sci.med.pathology
Date: Sat, 13 Apr 2019 19:53:14 -0700 (PDT)
Complaints-To: groups-abuse@google.com
Injection-Info: glegroupsg2000goo.googlegroups.com; posting-host=2001:56a:723e:aa00:947a:22f:c8ce:6d88;
posting-account=hBAG4AoAAABOaauYJdMbCKnI-qYy_97e
NNTP-Posting-Host: 2001:56a:723e:aa00:947a:22f:c8ce:6d88
User-Agent: G2/1.0
MIME-Version: 1.0
Message-ID: <6260d05f-0ea3-4a35-a232-5ab1a51a195d@googlegroups.com>
Subject: Iron And Lupus
From: teamtanner@hotmail.com (ironjustice)
Injection-Date: Sun, 14 Apr 2019 02:53:14 +0000
Content-Type: text/plain; charset="UTF-8"
Content-Transfer-Encoding: quoted-printable
Lines: 40
View all headers

The devil's in the dosing: severe drug-induced liver injury in a hydroxychloroquine-naive patient with subacute cutaneous lupus erythematosus and porphyria cutanea tarda
B Sunkara, D Roofeh, S Silver, ...
First Published April 9, 2018 Case Report
https://doi.org/10.1177/0961203318768884

Abstract
A 29-year-old woman with a 1.5 year history of photosensitive skin lesions on her hands presented with a malar rash, bullous lesions on her hands, and was diagnosed with subacute lupus erythematosus after serologies revealed a positive antinuclear antibody test (1:2560), and antibodies to Ro/SSA and dsDNA. Hydroxychloroquine (400 mg/day) was prescribed and the patient developed severe drug-induced liver injury. Biopsy of her bullous skin lesions was consistent with porphyria cutanea tarda, as were her serological and urinary exams. She was successfully treated with therapeutic phlebotomy. This case identifies porphyria cutanea tarda as an important differential diagnosis for the rheumatologist to consider when evaluating patients with bullous skin lesions. Hydroxychloroquine in lower doses is an effective treatment for porphyria cutanea tarda; at doses used to treat systemic lupus erythematosus and subacute cutaneous lupus, there is a potentially life-threatening complication of hepatotoxicity.

Keywords Systemic lupus erythematosus, drug-induced liver injury, hydroxychloroquine, porphyria cutanea tarda

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

1

rocksolid light 0.9.8
clearnet tor