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sci / sci.engr / Revolutionizing Biological Understanding: From Epigenetic Modulation to Innovative Water Absorption and Beyond

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o Revolutionizing Biological Understanding: From Epigenetic Modulation to InnovatiKay Lie

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Subject: Revolutionizing Biological Understanding: From Epigenetic Modulation to Innovative Water Absorption and Beyond
From: Kay Lie
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Date: Sat, 5 Aug 2023 16:08 UTC
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Subject: Revolutionizing Biological Understanding: From Epigenetic Modulation
to Innovative Water Absorption and Beyond
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What if you wanted to make a gomboch roller that could just keep on rolling, faster than a ball, if you are willing to have moveable masses at the interior of the gomboch and move them to a location furthest from gravitational minimal energy the gomboch will keep moving forward to try to be topside up, but thats always being updated so it just keeps rolling. there isn't motion without added energy, the G energy is matched with the power to the interior mass moving electromagnets. As a technology, they could make a car with just one drivecurve gomblob at the base meeting the surface. Its not so likely there will be a one moving contoured Gomcurve Tesla, but it is possible. Hey, its a public domain idea, they can make one if they feel like it..
making cooling towers more efficient, like
hyperbolic paraboloid )( nuclear plant cooling towers, i have not read anything about it but things that make very high surface area microripple waves could cause the water surface area underneath the likely sprayers to have an order of magnitude more surface area, facilitating evaporation, acoustics like beams could cause microspray droplets to wiggle and oscillate in the air to have much greater nonspherical length or flatness

I viewed an abstract where a molecule +(PPP) reduces schizophrenia symptoms 30%, but only lasts two weeks before the brain compensates and the PPP no longer works, that brings up the possibility of an antipsychotic that induces long lasting or permanent brain (dopamine receptor) compensation removing symptoms with long lasting induced tolerance to the body’s own dopamine receptor chemicals, it is possible, that just as JY gave me a drug that causes permanant dopamine receptor harm, permanenet receptor benefit is also possible, curing schizophrenia with one gradual build up dose over two weeks, phencyclidine might induce permanent psychosis, so a phencyclidine-variant with +(PPP) variant molecule might be such a molecule

also, you could put up hundreds of advertisements, except each would have a unique paragraph from me so fiver would like them

Immunization against deleterious tissue matrix peptides may heighten youthfulness of appearance, longevity, and healthspan, these peptidides described as matrikines, and described at this abstract copy material, “Extracellular matrix (ECM) proteins confer biomechanical properties, maintain cell phenotype and mediate tissue repair (via release of sequestered cytokines and proteases). In contrast to intracellular proteomes, where proteins are monitored and replaced over short time periods, many ECM proteins function for years (decades in humans) without replacement. The longevity of abundant ECM proteins, such as collagen I and elastin, leaves them vulnerable to damage accumulation and their host organs prone to chronic, age-related diseases. However, ECM protein fragmentation can potentially produce peptide cytokines (matrikines) which may exacerbate and/or ameliorate age- and disease-related ECM remodelling.” the genes that code these matrikines could also be epigenetically downregulated wi iRNA epigenetic methylation, possibly creating a single dose, or multicentury recurring iRNA dose from an injected or airjected depot material or implant, a heighten youthfulness of appearence, heightened longevity and heightened healthspan artificial or modified enhanced human gene could continuously make the epigenetic methylating iRNA as its gene product, creating a new human youthful appearance heightening, longevizing gene beneficial to make a component of an enhanced guman genome at all homo sapiens and branch species phenotypic as well as genotypic forms, also it is possible to have genes make peptides that occupy and block aging related matrikine peptidessuch that the receptors or cytochemistry activities are occupied fully, while being precluded from having any activity, causing heighten youthful appearance, and heightened duration of youthful appearance along with likely heightened longevity as a longevity technology

matrikines are described as modifying the matrix materials of cytes, tissues, body structures, and likely organs, just as some matrikines are published as linked to deleterious or senescent like effects, it is possible that genetically or epigenetically upregulating matrix physiomolecules such as proteins and other molecules amount or type is beneficial, with some genes and gene variants possibly based on supercentenarians of unusually youthful appearance after puberty could be a thing to base matrix physioomolecules on as a longevity technology

Longevity technology, precision demethylation epigenetic modulators utilizable at a single gene nucleotide sequence are published at 2023 and 2022AD, these then upregulate the genes that het demthylated. Rather like all the locations where I note acetylation longevity technolofies are posssible, demethylation upregulation longevity technologies are possible at such thinhs at the klotho gene, dna rapair genes, antioxidant genes, ampk genes and mny others being precision dememethylated.

An epigenetic therapy for EtOH nonompimality preclusion is just using the precision demethylation crispr-gsDNA epigenetic editing technology published at 2023AD, alcohol dehydrogenase could be epigenetically upregulated from demethylation, this would make ceasing EtOH easier because it is metabolized much faster, and could also prevent EtOH based birth defects

it is possible that some human epigenetic modulator production could come from result of a challenge, and like hormesis, the strength of the reaction causing greater wellness, I do not think there is such a mechanism, but imagine if a response to high blook pressure was to have the body make its own epigenetic modulator of blood pressure, reducing blood pressure the entire lifespan, from a single high blood pressure occurence. That is beneficial hormeisis

Epigenetic modulators that cause optimal blood pressure could be new drugs like iRNA epigenetic modulators that heighten lifespan, cause reduction of cardiovascular illness, and sustain mental wellness, one abstract notes that, “hypermethylation of NFKB1 gene was significantly associated with reduced blood pressure in obese patients after RYGB” iRNA could do that methylation

as a sex and oral sex enhancement technology, oral peptides that stimulate the taste receptors are a possible oral pill that enhances sexual enjoyment and oral sex, sweetness peptides are published, and I think butter on white rice, ranch dressing similar, and onion, or garlic similar taste sensation peptides, and kiwi or melon fruit flavor peptides are also possible as oral pills, this heightens enjoyment and durationof cunnilingus, and makes male semen and sperm ejaculate delicious

I read about a hydrogen generation from electrolysis of water catalyst that heightened efficiency 50%, perhaps a similar catalyst could heighten value effective concentration of elements from electrochemical treatment of heap leachate fluids

On the internet I published with a tweet, “I would have liked to have had multiple children. If you like you can get genetically advantaged sperm and eggs from sperm banks and egg donor companies. Companies even advertise at MIT to find women to donate eggs so you'll have smart, capable, beautiful mentally well daughters.” I am particularly enthused about people with higher Light Triad Psychometric enumerative measure of light triad attributes than I have, notably above 80th 2022AD percentile, as well as people more cognitively capable than I am having more children voluntarily..

mRNA drugs that get translated to gene products like proteins and other products, could, if halogenated as medical molecules resist metabolism much longer, and so be translated to gene products lots more times, kind of imitating epigenetic acetylation

Factor 8 lack is linked to hemophilia and reduced blood clotting, it could be that there are human gene variants or alleles that provide fully functional blood clotting, with 98th percentile leasth autogenerative occurence of making thrombosis clots at the circulatory system, persons with those gene variants would then have much descreased cardiovascular illness, strokes, and thrombosis chunk ischemia events at the heart and other areas of the body, finding those human alellele variants, then enhancing the human genome to have those, as well as making a gene therapy technology then causes humans to be at the 98th percentile least thrombosis chunk production while being absent hemophilia, it is possible that could cause a reduction of strokes and heart attacks to some single digit % amount of the occurence of strokes and heart attacks at 2022AD humans, also epigenetic modulation of clotting factors could be beneficial to cause least thrombosis formation completely absent hemophelia

arthritis might be reducible using the way putting a phosphatidyl moiety actually makes the body less imuunoreactive to that base molecule, phosphorylated ligaments, joints, and tendons as macroscopic homogenates could then be administered with liposomes, or injected into lympth nodes to prevent the occurenence or spread of arthritis.

I have read that ic making photoresists use EUV light for minute feature size, a way to use an order of magnitude less EUV light intensity and be more affordable is to blend 1/2 nm or more minute quantum dots with the photoresist polymer, then RF/photon energize the quantum dot photopolymer to just less than an exposure amount of enegy, such that much less intense EUV beams are able to expose the photoresist.

bone growth plates fuse from estrogen, whch contributed to women being less tall than men at 2022AD, epigenetic modulators that downregulate the production of estrogen receptors at bone growth plates then make it such that developing girls and women with just two sex chromosomes both of them X sex chromosomes develop to have atll 73 or 74 inch heights, one eipigenetic modulator that could do this is acetylating iRNA


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